Storyline
Discover the story behind the screen.
Dr. Lily Houghton enlists the aid of wisecracking skipper Frank Wolff to take her down the Amazon in his dilapidated boat. Together, they search for an ancient tree that holds the power to heal – a discovery that will change the future of medicine.
Top Billed Cast
Dwayne Johnson
Frank Wolff
Emily Blunt
Dr. Lily Houghton
Edgar Ramírez
Lope de Aguirre
Jack Whitehall
McGregor Houghton
Jesse Plemons
Prince Joachim
Paul Giamatti
Nilo Nemolato
Veronica Falcón
Trader Sam
Dani Rovira
Sancho
Quim Gutiérrez
Melchor
D
Dan Dargan Carter
Gonzalo
Andy Nyman
Sir James Hobbs-Coddington
Raphael Alejandro
Zaqueu
Simone Lockhart
Anna
Pedro Lopez
Chief
